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| Product Name | BEST1, Recombinant, Human, aa292-585, His-Tag (Bestrophin-1 Isoform 1) |
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| Description | Purity ~90% (SDS-PAGE). BEST1 is a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Source: Recombinant corresponding to aa292-585 from human BEST1 protein, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~36kD (317aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_004174 |
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| Catalog # | 217973 |
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| Order / More Info | BEST1, Recombinant, Human, aa292-585, His-Tag (Bestrophin-1 Isoform 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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