| 产品详情 |
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| Product Name | IWP-3 |
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| Description | MW: 484.59. Purity ≥98%. Background: An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro (IC?? = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC?? = 1.2 muM). |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Inhibitor of Wnt Production-3; 2-?[[3-?(4-?fluorophenyl)-?3,?4,?6,?7-?tetrahydro-?4-?oxothieno[3,?2-? d]pyrimidin-?2-?yl]thio]-?N-?(6-?methyl-?2-?benzothiazolyl)-?acetamide] |
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| Gene, Accession, CAS # | CAS: 687561-60-0 |
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| Catalog # | MBS842580 |
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| Price | |
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| Order / More Info | IWP-3 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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