| 产品详情 |
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| Product Name | IWP-3 |
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| Description | Purity >98%. An inhibitor of Wnt production. Blocks Wnt pathway activity in vitro ( IC50 = 40 nM). IWP-3 inactivates Porcupine (Porcn), a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. Through blockade of Wnt signaling, IWP-3 has been used to promote cardiomyocyte generation from human embryonic stem cells (EC50 = 1.2 MM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[3-(4-fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2- d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide, Inhibitor of Wnt Production-3 |
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| Gene, Accession, CAS # | CAS: 687561-60-0 |
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| Catalog # | LS-H2924 |
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| Order / More Info | IWP-3 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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