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| Product Name | AI-3 |
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| Description | Purity >98% by NMR, TLC. AI-3 is an activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. AI-3 activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo. MP = 71-74°C |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one |
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| Gene, Accession, CAS # | CAS: 882288-28-0 |
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| Catalog # | LS-H14490 |
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| Order / More Info | AI-3 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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