| 产品详情 |
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| Product Name | AICAR |
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| Description | MW: 258.2. Purity >98% (TLC); NMR (Conforms). AMPK activatorNovel, selective ATP-competitive inhibitor of Aurora B kinase in vitro (IC50 values are 50, 250 and 1000 nM for Aurora B, C and A kinases respectively). Selective over a range of other kinases including cdk1 and PLK1 (IC50 > 10 uM). Inhibits cell division and displays selective toxicity towards proliferating tumor cells versus non-dividing cells.Scientific Background: Activates AMP-activated protein kinase (AMPK). Pro |
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| Size | 10 mg, 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ZM-447439; N-[4-[[6-Methoxy-7-[3-(4-morpholiny~l)propoxy]-4-quinazolinyl]amino]phenyl]benzamide] |
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| Gene, Accession, CAS # | CAS: 2627-69-2 |
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| Catalog # | MBS515046 |
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| Order / More Info | AICAR from MYBIOSOURCE INC. |
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| Product Specific References | 1. C Ditchfield et al J. Cell Biol. 2003 161:267 2. F Girdler et al J. Cell Sci. 2006 119:3664 3. F H Jung et al J. Med. Chem. 2006 49:955 |
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