| 产品详情 |
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| Antigenic Specificity | CNN1 / Calponin |
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| Clone | CNN1/1408R |
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| Host Species | Recombinant Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A/G purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC-Fx, SDS-PAGE |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CNN1 / Calponin Antibody (clone CNN1/1408R) LS-C751109. Specificity: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. |
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| Immunogen | Recombinant full-length human CNN1 protein. Antigen Molecular Weight: 34 kDa |
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| Other Names | CNN1, Basic calponin, Calponin, Calponin-1, Calponins, basic, Calponin H1, smooth muscle, SMCC, Sm-Calp |
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| Gene, Accession # | CNN1, Gene ID: 1264 |
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| Catalog # | LS-C751109 |
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| Price | |
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| Order / More Info | CNN1 / Calponin Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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