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Product Name | GW 0742 |
Description | Potent and highly selective PPARδ agonist. EC50 values are 0.001, 1.1 and 2 μM for transactivation of human PPARδ, -α, and -γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes. Purity 98%. MW (observed): 471.49 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]acetic acid |
Gene, Accession, CAS # | CAS: 317318-84-6 |
Catalog # | 2229/50 |
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Order / More Info | GW 0742 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19818482, 22606221, 22933110, 23716627, 24817882, 25116175, 25485183, 26508837, 26630504, 28539839 |
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