产品详情 |
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Product Name | GW 2580 |
Description | Potent and selective cFMS kinase inhibitor (IC50 = 0.06 μM). Exhibits selectivity for cFMS kinase over 186 other kinases. Inhibits CSF-1-induced growth of rat monocytes in vitro. Also inhibits bone resorption in osteoclast cultures, as well as connective tissue and bone destruction in a rat adjuvant arthritis model. Suppresses M-NFS-60 tumor cell growth in mice. Orally bioavailable. Purity 99%. MW (observed): 366.41 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine |
Gene, Accession, CAS # | CAS: 870483-87-7 |
Catalog # | 5673/10 |
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Order / More Info | GW 2580 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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