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Product Name | GW 4064 |
Description | Selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM). Displays no activity at other nuclear receptors at concentrations up to 1 μM. Improves hyperglycaemia and hyperlipidemia in diabetic db/db mice. Shown to suppress autophagy in nutrient-deprived mouse hepatocytes. Purity 97%. MW (observed): 542.84 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid |
Gene, Accession, CAS # | CAS: 278779-30-9 |
Catalog # | 2473/50 |
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Order / More Info | GW 4064 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 19910507, 21220320, 21988803, 23688559, 24033844, 24335393, 24498423, 24953769, 25383539, 25400456, 26888176, 26950211, 27869139, 28351411, 29643332 |
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