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| Product Name | PGD, Recombinant, Human, aa1-483, His-Tag (Phosphogluconate Dehydrogenase, 6PGD) |
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| Description | Purity ~90% (SDS-PAGE). PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483aa enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. Source: Recombinant protein corresponding to aa1-483 from human PGD, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~55.3kD (503aa) Specific Activity: >10units/mg, one unit oxidize 1umole of 6-phospho-D-gluconate to D-ribulose 5-phosphate/minute at pH 8.0 at 25°C, in the presence of beta-NADP. AA |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_002622 |
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| Catalog # | 351430 |
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| Order / More Info | PGD, Recombinant, Human, aa1-483, His-Tag (Phosphogluconate Dehydrogenase, 6PGD) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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