| 产品详情 |
| Edit |   |
|---|
| Product Name | Paraoxonase-1, Recombinant, Human, His-Tag |
|---|
| Description | Highly Purified (~95%). Paraoxonase 1, also called Esterase-A, is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase 1 may also confer protection against coronary artery disease by destroying proinflammatory oxidized lipids present in oxidized low-density lipoproteins (LDLs). PON was identified as an enzyme having organophosphates as its substrates. Reports of the geographic differences in population frequencies of paraoxonase activity and genetic analysis led to uncovering the genetic polymorphism. There are 3 known genotypic forms of paraoxonases. They are coded for by the PON set of genes-PON1, PON2 and PON3-located on the long arm of chromosome 7. The differences between them lie in their location and activity. PON1 is synthesized in the liver and transported along with HDL in the plasma. It functions as an antioxidant; it prevents the oxidation of LDL. Its serum concentration is influenced by inflammatory changes and the levels of serum o |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | ELISA WB |
|---|
| Other Names | Paraoxonase-1, Recombinant, Human, His-Tag (Esterase-A, Serum Paraoxonase, Arylesterase 1, EC 3.1.1.2, EC 3.1.8.1, PON 1, Serum Aryldialkylphosphatase 1, A-esterase 1, Aromatic Esterase 1, K-45, ESA, PON) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 209130 |
|---|
| Price | |
|---|
| Order / More Info | Paraoxonase-1, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|