| 产品详情 |
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| Product Name | Pep-1 (uncapped) |
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| Description | Purity >95%. PEP-1 peptide;which has 21 amino acid residues;is a known carrier peptide that delivers full-length native proteins in vitro and in vivo. Pep-1 peptide;consists of three domains: (1) a hydrophobic tryptophan-rich motif containing five tryptophan residues (KETW WETWWTEW);(2) a hydrophilic lysine-rich domain (KKKRKV) derived from the nuclear localization sequence (NLS) of simian virus 40 (SV-40) large T antigen;and (3) a spacer domain (SQP);separating the two domains mentioned above;containing a proline residue;which improves the flexibility and the integrity of both the hydrophobic and the hydrophilic domains. In standard cell culture conditions;Pep-1 localizes rapidly;in <10 min;to the nucleus of human HS-68;murine NIH-3T3 fibroblasts;or Cos cells. Similar experiments;performed by incubating cells for 30 min at 4°C before transfection;yielded essentially the same result;indicating that Pep-1 internalization is independent of normal endocytosis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Lys-Glu-Thr-Trp-Trp-Glu-Thr-Trp-Trp-Thr-Glu-Trp-Ser-Gln-Pro-Lys-Lys-Lys-Arg-Lys-Val |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H4682 |
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| Price | |
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| Order / More Info | Pep-1 (uncapped) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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