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Antigenic Specificity | Claudin 2/CLDN2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100ug (sample available) |
Concentration | 500ug/ml. |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Claudin-2(CLDN2) detection. Tested with WB, IHC-P in Human;Rat. No cross reactivity with other proteins. Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter. |
Immunogen | E.coli-derived human Claudin 2 recombinant protein (Position: A38-V230). Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2. |
Other Names | Claudin-2;SP82;CLDN2;PSEC0059, SP82, UNQ705/PRO1356; |
Gene, Accession # | CLDN2, UniProt: P57739 |
Catalog # | RP1042 |
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Order / More Info | Claudin 2/CLDN2 Antibody from BOSTER BIO |
Product Specific References | n/a |
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