| 产品详情 |
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| Antigenic Specificity | Hsp105/HSPH1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Heat shock protein 105 kDa(HSPH1) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat. No cross reactivity with other proteins. HSP105(HEAT-SHOCK 105/110-KD PROTEIN 1), also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13. Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides, HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Hsp105(713-733aa EVMEWMNNVMNAQAKKSLDQD), different from the related mouse sequence by one amino acid, and different from the related rat sequence by two amino acids. |
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| Other Names | Heat shock protein 105 kDa;Antigen NY-CO-25;Heat shock 110 kDa protein;HSPH1;HSP105, HSP110, KIAA0201; |
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| Gene, Accession # | HSPH1, UniProt: Q92598 |
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| Catalog # | PA1608 |
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| Price | |
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| Order / More Info | Hsp105/HSPH1 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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