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| Product Name | BUB3, Recombinant, Human, aa1-328, His-Tag (Mitotic Checkpoint Protein BUB3, BUB3L, hBUB3) |
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| Description | Purity ~85% (SDS-PAGE). Mitotic checkpoint protein BUB3, also known as BUB3, is a conserved component of the mitotic spindle assembly complex (MCC). The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. Source: Recombinant protein corresponding to aa1-328 from human BUB3 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~39.5kD (351aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTGSNEF KLNQPPEDGI SSVKFSPNTS QFLLVSSWDT SVRLYDVPAN SMRLKYQHTG AVLDCAFYDP THAWSGGLDH QLKMHDLNTD QENLVGTHDA PIRCVEYCPE VNVMVTGSWD QTVKLWDPRT PCNAGTFSQP EKVYTLSVSG DRLIVGTAGR RVLVWDLRNM GYVQQRRESS LKYQTRCIRA FPNKQGYVLS SIEGRVAVEY LDPSPEVQKK KYAFKCHRLK ENNIEQIYPV NAI |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138616 |
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| Order / More Info | BUB3, Recombinant, Human, aa1-328, His-Tag (Mitotic Checkpoint Protein BUB3, BUB3L, hBUB3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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