| 产品详情 |
| Edit |   |
|---|
| Product Name | NFNB, Recombinant, E.coli |
|---|
| Description | Purity ~95% (SDS-PAGE). NFNB, also known as NFSB, shows the ability to reduce quinines. This protein is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species. Source: Recombinant corresponding to aa1-217 of E.coli NFNB protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV Molecular Weight: 26kD (237aa) confirmed by MALDI-TOF Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | NFNB, Recombinant, E.coli (Oxygen-insensitive NAD(P)H Nitroreductase, Dihydropteridine Reductase, FMN-dependent Nitroreductase, nfnB, dprA, nfsB, nfsI, ntr, b0578, JW0567) |
|---|
| Gene, Accession, CAS # | Accession: NP_415110 |
|---|
| Catalog # | N2350-60 |
|---|
| Price | |
|---|
| Order / More Info | NFNB, Recombinant, E.coli from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|