| 产品详情 |
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| Product Name | Topiramate |
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| Description | Anticonvulsant. Antagonizes GluK1 (formerly GluR5) kainate receptors (IC50 = 0.46 μM), acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH. Deuterated analog also available. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions. Purity 99%. MW (observed): 339.36 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate. Topamax |
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| Gene, Accession, CAS # | CAS: 97240-79-4 |
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| Catalog # | 3620/10 |
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| Price | |
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| Order / More Info | Topiramate from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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