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| Product Name | Lovastatin |
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| Description | Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Indirectly inhibits Rho-GTPase activity by depleting intracellular pool of isoprene residues. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Inactive lactam prodrug of lovastatin hydroxy acid, naturally bioactivated in vivo following oral administration. Purity 98%. MW (observed): 404.54 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate. Mevinolin |
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| Gene, Accession, CAS # | CAS: 75330-75-5 |
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| Catalog # | 1530/10 |
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| Price | |
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| Order / More Info | Lovastatin from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22202492, 22710979, 23892605, 24489942, 24762141, 25945415, 26501302, 27270401 |
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