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| Product Name | Recombinant Mouse Tyrosine-protein kinase JAK3 |
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| Description | 818-1100aa; Partial. MW: 36.3kD. Purity >90% as determined by SDS-PAGE. Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hatopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Janus kinase 3; JAK-3] |
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| Gene, Accession, CAS # | Jak3, Gene ID: 16453, Accession: NP_001177759.1 |
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| Catalog # | MBS1359679 |
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| Order / More Info | Recombinant Mouse Tyrosine-protein kinase JAK3 from MYBIOSOURCE INC. |
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| Product Specific References | JAK3 a novel JAK kinase associated with terminal differentiation of hematopoietic cells.Rane S.G., Reddy E.P.Oncogene 9:2415-2423(1994) Murine JAK3 is preferentially expressed in hematopoietic tissues and lymphocyte precursor cells.Gurniak C.B., Berg L.J.Blood 87:3151-3160(1996) Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells.Witthuhn B.A., Silvennoinen O., Miura O., Lai K.S., Cwik C., Liu E.T., Ihle J.N.Nature 370:153-157(1994) Defects i |
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