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| Product Name | Recombinant Human Importin subunit alpha-1 |
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| Description | 8-528aa; Partial. MW: 63.6kD. Purity >90% as determined by SDS-PAGE. Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechani |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (Baculovirus), 0.2 mg (E-Coli), 0.2 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Karyopherin subunit alpha-2; RAG cohort protein 1; SRP1-alpha] |
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| Gene, Accession, CAS # | KPNA1, Gene ID: 3838, Accession: NP_002257.1 |
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| Catalog # | MBS1159901 |
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| Order / More Info | Recombinant Human Importin subunit alpha-1 from MYBIOSOURCE INC. |
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| Product Specific References | Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences.Weis K., Mattaj I.W., Lamond A.I.Science 268:1049-1053(1995) |
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