| 产品详情 |
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| Antigenic Specificity | S100 Protein |
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| Clone | 6G1 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | S100 Protein Antibody (clone 6G1) LS-C58307. Recognizes S100 protein derived from human brain tissue. It is a 21kD acidic calcium-binding protein synthesized by astroglial cells. It can be found predominantly as two isoforms, the alpha-beta heterodimer (S100a) and the beta-beta homodimer (S100b). The S100 family of proteins have been implicated in a large variety of intracellular and extracellular regulatory activities, such as cellular energy metabolism, cytoskeleton modification, cell proliferation and differentiation. When glial cells are damaged, S100 protein is leaked into the extracellular matrix and cerebrospinal fluid, further releasing into the bloodstream. As such, S100 protein can be used as a sensitive and reliable marker for nervous system damage, such as after brain damage or acute stroke. Recognizes both S100a (alpha-beta) and S100b (beta-beta). May be used to detect S100 protein in ELISA assay. Sensitive to EDTA and other bivalent-binding agents. Better performance can be obtained in the presence of 5 mM CaCl2 in assay buffers. |
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| Immunogen | Human brain S100 protein. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | LS-C58307 |
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| Price | |
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| Order / More Info | S100 Protein Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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