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| Product Name | CHK2, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). CHK2 is rapidly phosphorylated and activated in response to replication blocks and DNA damage; the response to DNA damage occurs in an ataxia telangiectasia mutated (ATM)-dependent manner. Expression of wild-type Chk2 leads to increased p53 stabilization after DNA damage, whereas expression of a dominant-negative Chk2 mutant abrogated both phosphorylation of p53 on Ser-20 and p53 stabilization. Source: Recombinant protein corresponding to human CHK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~88kD Specific Activity: 808nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CHK2, Recombinant, Human, GST-Tag (CHK2 Checkpoint Homolog (S. Pombe), CDS1, CHEK2, HuCds1, LFS2, PP1425, RAD53) |
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| Gene, Accession, CAS # | Accession: NM_007194 |
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| Catalog # | 499884 |
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| Price | |
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| Order / More Info | CHK2, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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