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| Product Name | PNP, 1-289aa, Human, His tag, E.coli (Bioactivity Validated) |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 2mM DTT, 10% glycerol . PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2'-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | Enzyme activity |
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| Other Names | Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PuNP |
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| Gene, Accession, CAS # | NP 000261 |
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| Catalog # | ATGP0786 |
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| Order / More Info | PNP, 1-289aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen |
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| Product Specific References | n/a |
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