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| Product Name | FasL, Soluble, Recombinant, Human, aa139-281 |
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| Description | Purity ~95% (SDS-PAGE). Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development. Source: Recombinant protein corresponding to aa139-281 from human FasL, fused at the N-terminal to the Fc portion of human IgG1, expressed in HEK 293 cells. Molecular Weight: ~50kD (SDS-PAGE) Biological Activity: Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml. Endotoxin: <0.01EU/ug purified protein (LAL test; Lonza) |
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| Size | 10ug, 3x10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FasL, Soluble, Recombinant, Human, aa139-281 (Apoptosis Antigen Ligand, APT1LG1, APTL, CD95 Ligand, CD95L, CD95-L, FAS Antigen Ligand, Fas Ligand, CD178, FASLG, Tumor Necrosis Factor Ligand Superfamily Member 6, TNFSF6) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207170 |
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| Order / More Info | FasL, Soluble, Recombinant, Human, aa139-281 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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