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| Product Name | Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Recombinant, Human |
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| Description | Purity ~ 95% (SDS-PAGE). Purified by using conventional chromatography techniques. SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protein is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E. coli. Source: Recombinant corresponding to aa1-313 of human SGTA 6x His tagged expressed in E. coli. AA Sequence: MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEE |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Recombinant, Human (SGTA, Alpha-SGT, alphaSGT, hSGT, SGT, SGT1, UBP, Vpu-binding Protein) |
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| Gene, Accession, CAS # | Accession: NP_003012 |
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| Catalog # | S1014-58P7 |
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| Order / More Info | Small Glutamine-rich Tetratricopeptide Repeat-containing Protein alpha, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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