产品详情 |
Edit |   |
Product Name | 3PO |
Description | Originally reported to inhibit PFKFB3 (IC50 = 25 μM). More recent reports failed to demonstrate activity in a PFKFB3 kinase assay. Reduces glycolytic flux and suppresses glucose uptake. Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro. Attenuates vessel sprouting and tumor growth in vivo. Amplifies the antiangiogenic effect of VEGFR blockade. Purity 99%. MW (observed): 210.23 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one |
Gene, Accession, CAS # | CAS: 13309-08-5 |
Catalog # | 5121/50 |
Price | |
Order / More Info | 3PO from TOCRIS BIOSCIENCE
|
Product Specific References | n/a |
产品资料 |
|
|