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| Product Name | 1-Deoxynojirimycin (hydrochloride) |
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| Description | Purity >95%. 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits Alpha-glucosidase I and II. It prevents the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells by inhibiting both Alpha-glucosidase I and II with IC50 values of ~2 µM. The FDA has granted orphan drug designation to dNM (hydrochloride) for the treatment of Pompe disease, an inherited lysosomal storage disorder caused by a mutation that alters the structure and stability of Alpha-glucosidase. 1-dNM, at a concentration of 0.4 mM, also inhibits virus spread in HIV-infected lymphocyte cultures by interfering with Alpha-glucosidase activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol, monohydrochloride, Moranoline, 1-dNM |
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| Gene, Accession, CAS # | CAS: 73285-50-4 |
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| Catalog # | LS-H5888 |
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| Order / More Info | 1-Deoxynojirimycin (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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