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| Product Name | SOCS-3, Recombinant, Human |
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| Description | Purity >90% (SDS-PAGE). SOCS-3 is an SH2-containing protein predominantly expressed in T-helper type 2 cells, that binds to the activation loop of Janus kinases, inhibiting the kinase activity and thereby suppressing cytokine signaling. SOCS-3 therapy may be useful in the treatment of cancer. SOCS-3 has an important role in regulating the onset and maintenance of TH2-mediated allergic immune disease and is a new therapeutic target for antiallergic drugs. Sequence: Human SOCS-3 (aa 1-225) is fused at the C-terminus to a His-tag. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SOCS-3, Recombinant, Human (His) (CIS-3, Cytokine-inducible SH2-containing Protein-3, SSI-3, Suppressor of Cytokine Signaling-3, SOCS 3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45307 |
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| Order / More Info | SOCS-3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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