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| Product Name | Fractalkine, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). Fractalkine is a type I membrane protein that signals through the CX3CR1 receptor. The extracellular domain of Fractalkine is released by protease cleavage - producing soluble Fractalkine. Fractalkine has been found in many tissues and shown to be up-regulated in endothelial cells and microglia in response to inflammatory signals. Fractalkine is also involved in leukocyte adhesion as well as attracting monocytes, microglia cells and NK cells. Source: Recombinant protein corresponding to human Fractalkine expressed in E. coli. Molecular Weight: ~8.9kD Biological Activity: Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CX3CR1, the ED50 for this effect is typically 20-100ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Fractalkine, Recombinant, Human (C-X3-C Motif Chemokine 1, CX3C Membrane-Anchored Chemokine, Neurotactin, Small-Inducible Cytokine D1, CX3CL1) |
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| Gene, Accession, CAS # | SwissProt: P78423 |
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| Catalog # | 500023 |
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| Order / More Info | Fractalkine, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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