| 产品详情 |
| Edit |   |
|---|
| Product Name | Go6976 (ATP-competitive PKC Inhibitor Specific for Ca2+-dependent PKCalpha and PKCBeta1) |
|---|
| Description | Purity ~95%. Go6976 is an ATP-competitive PKC inhibitor specific for Ca2+-dependent PKCalpha (IC50= 2.3nM) and PKCBeta1 (IC50 = 6.2nM) isozymes (1). It is also a potent inhibitor of PKD (IC50= 20nM) (2). Researchers have demonstrated that Go6976 blocks JNK activation (3-5) and inhibits PKCalpha-mediated, TPA-stimulated phosphorylation of CREB at Ser133 (6,7). Go6976 is also an effective inhibitor of the tyrosine kinases Jak2 and FLT3 (8), as well as TrkA and TrkB (9). Solubility: ~25mg/ml (DMSO). |
|---|
| Size | 500ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 137438 |
|---|
| Price | |
|---|
| Order / More Info | Go6976 (ATP-competitive PKC Inhibitor Specific for Ca2+-dependent PKCalpha and PKCBeta1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|