| 产品详情 |
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| Product Name | Neoandrographolide |
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| Description | Purity >95%. Neoandrographolide is one of the principle diterpenoids isolated from A. paniculata, a well-recognized medicinal plant in Asia. Extracts from A. paniculata have been reported to exert a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities. Neoandrographolide has been shown to inhibit LPS-induced nitric oxide production in inflammatory macrophages after oral administration to mice (25 mg/kg) or by direct addition to cultured macrophages (IC50 = 35.5 µM). At 25 µM, it can reduce VEGF-induced proliferation of human umbilical vein endothelial cells. Neoandrographolide also inhibits the pro-protein convertase furin with an IC50 value of 53.5 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[2-[(1R,4aS,5R,8aS)-5-[(Beta-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone |
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| Gene, Accession, CAS # | CAS: 27215-14-1 |
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| Catalog # | LS-H8959 |
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| Order / More Info | Neoandrographolide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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