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| Product Name | GDNF BioAssay™ ELISA Kit, Human |
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| Description | Sandwich ELISA quantitative detection kit for Human GDNF in cell culture supernates, serum and plasma (heparin, EDTA). Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily.1 GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures.2 GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.1 GDNF lies on the short arm of human chromosome 5, at 5p13.1-p13.3 ability to promote dopamine uptake in midbrain cultures.2 Assay Range: 31.2pg/ml-2000pg/ml Sensitivity: < 4 pg/ml Crossreactivity: Ther |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 2668, SwissProt: P39905 |
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| Catalog # | 143850 |
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| Order / More Info | GDNF BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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