| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | SELL / L-Selectin / CD62L |
|---|
| Clone | FMC46 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | bovine, human, cynomolgus monkey, rhesus monkey |
|---|
| Isotype | IgG2b |
|---|
| Format | fluorescein (FITC) conjugate |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | Flo (1:1), IHC, IHC-Fr, IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | SELL / L-Selectin / CD62L Antibody (clone FMC46, FITC) LS-C43267. Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naA-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation. |
|---|
| Immunogen | PHA stimulated lymphoblasts. |
|---|
| Other Names | SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor |
|---|
| Gene, Accession # | SELL, Gene ID: 6402 |
|---|
| Catalog # | LS-C43267 |
|---|
| Price | |
|---|
| Order / More Info | SELL / L-Selectin / CD62L Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|