| 产品详情 |
| Edit |   |
|---|
| Product Name | Insulin Receptor Substrate 1, Y612, Control Peptide (IRS-1) |
|---|
| Description | Purity ~90% by HPLC and MS analysis. Insulin receptor substrate useful in phosphocellulose assay. Insulin Receptor Substrate-1 (IRS-1) is a major endogenous substrate for the insulin receptor and IGF-1R tyrosine kinase. Although IRS-1 is constitutively phosphorylated on serine and threonine, it is tyrosine-phosphorylated only after stimulation by insulin. The tyrosine phosphorylated IRS-1 serves as the major agent of insulin receptor-mediated signal transduction by being bound by cytoplasmic signaling proteins containing SH2 domains. Numerous SH2-containing signaling proteins (e.g., Grb2, SH-PTP2/SYP, PI-3-Kinase, and NCK) are known to preferentially bind to distinct tyrosine phosphorylation sites on IRS-1. Sequence (linear): H2N-Lys-Lys-His-Thr-Asp-Asp-Gly-Tyr-Met-Pro-Met-Ser-Pro-Gly-Val-Ala-OH Amino Acid Analysis: Confirms expected sequence Peptide Content: 80.0 ± 4% Solubility: H2O |
|---|
| Size | 1mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | I7661-27B |
|---|
| Price | |
|---|
| Order / More Info | Insulin Receptor Substrate 1, Y612, Control Peptide (IRS-1) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|