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| Product Name | MIF, Recombinant, Mouse |
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| Description | Purity ~95% (SDS-PAGE). Macrophage Migration Inhibitory Factor (MIF) is a proinflammatory cytokine which is involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. Source: Recombinant protein corresponding to mouse MIF expressed in E. coli. Molecular Weight: ~15kD Biological Activity: The ED50 was determined by the dose-dependent proliferation of HTB9 cells and was found to be <0.5ng/mL. Endotoxin: <1EU/ug (LAL) |
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| Size | 25ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MIF, Recombinant, Mouse (Delayed Early Response Protein 6, DER6, Glycosylation-Inhibiting Factor, GIF, L-Dopachrome Isomerase, L-Dopachrome Tautomerase, EC=5.3.3.12, Phenylpyruvate Tautomerase, Macrophage Migration Inhibitory Factor) |
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| Gene, Accession, CAS # | SwissProt: P34884 |
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| Catalog # | 500260 |
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| Order / More Info | MIF, Recombinant, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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