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| Product Name | Neurite Outgrowth Inhibitor Protein B, Rat (Nogo-B) (Control Peptide) |
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| Description | Highly purified. Control peptide for N2116-42 (affinity purified antibody) and N2116-43 (antiserum). Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrowafter injury. The CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyses. An inhibitory myelin protein, Nogo (Neurite outgrowth), has been cloned and characterized. It may help block the regeneration of the CNS. Nogo is the 4th member of reticulon (Rtn) family. There are three alternative isoforms of Nogo. Nogo-A is full length human protein consisting of 1192aa, Mr ~135kD (rat 1163aa). Nogo-B is an intermediate form consistiong of 373aa, ~37kD. Nogo-B lacks aa186-1004 within the extracellular domain. Nogo-C is shorter consisting of 199aa, ~25kD. It lacks aa186-1004 and has a smaller, alternative N-terminal domain. It is similar to rat vp20 and foocen-s. Nogo-A has a putative extracellular domain of 1024aa, 2-3 TM do |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2116-41 |
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| Order / More Info | Neurite Outgrowth Inhibitor Protein B, Rat (Nogo-B) (Control Peptide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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