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| Product Name | Neuritin, Recombinant, Human (NRN1, NRN, dJ380B8.2, MGC44811) |
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| Description | Purity ~98% (SDS-PAGE and HPLC). Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.7kD polypeptide monomers, each containing 88aa. Source: Recombinant protein corresponding to human Neuritin, expressed in E.coli. Biological Activity: Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20-30ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MAGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149735 |
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| Order / More Info | Neuritin, Recombinant, Human (NRN1, NRN, dJ380B8.2, MGC44811) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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