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| Product Name | SU-4312 |
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| Description | MW: 264.3. Purity >98% (TLC); NMR (Conforms). VEGFR; PDGFR inhibitorScientific Background: Potent and selective inhibitor of VEGF receptor tyrosine kinase (Flk-1, KDR). Inhibits unactivated kinase 100-fold greater (IC50=0.04 uM) than activated kinase (IC50=4.0 uM) (1). Weak inhibitor of PDGF receptor tyrosine kinase (IC50=19.4 uM) (2). Inhibits endothelial cell activation and angiogenesis in a mouse model of Alzheimers disease (3). |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [PP2] |
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| Gene, Accession, CAS # | CAS: 172889-27-9 |
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| Catalog # | MBS515079 |
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| Order / More Info | SU-4312 from MYBIOSOURCE INC. |
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| Product Specific References | 1. RL Kendall et al. J. Biol. Chem. 1999 274:6453 2. L Sun et al. J. Med. Chem. 1998 41:2588 3. Schultheiss et al. Angiogenesis 2006 9:59 |
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