| 产品详情 |
| Edit |   |
|---|
| Product Name | BAZ2B, Bromodomain, recombinant, Human, aa2064-2168, GST-tag |
|---|
| Description | Purity ~80% (SDS-PAGE). The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. BAZ2B is expressed in heart, skeletal, testis, and pancreatic tissues. A rare allele of BAZ2B has been identified to be a predictor of Sudden Cardiac Death.4 The full-length protein contains several DNA-targeting domains, including a methyl-CpG binding domain, a DNA-binding DDT domain, and a tandem PHD-bromodomain. This protein product contains the bromodomain of BAZ |
|---|
| Size | 20ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | BAZ2B, Bromodomain, recombinant, Human, aa2064-2168, GST-tag (Bromodomain Adjacent to Zinc Finger Domain 2B, KIAA1476, WALp4) |
|---|
| Gene, Accession, CAS # | BAZ2B, Gene ID: 29994, SwissProt: Q9UIF8 |
|---|
| Catalog # | 219446 |
|---|
| Price | |
|---|
| Order / More Info | BAZ2B, Bromodomain, recombinant, Human, aa2064-2168, GST-tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|