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| Product Name | Recombinant Human Tyrosine-protein kinase ABL1 |
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| Description | 4-194. Partial. MW: 48.5kD. Purity >90% as determined by SDS-PAGE. Non-receptor tyrosine-protein kinase that plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like WASF3 (involved in branch formation); ANXA |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Ablp150] |
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| Gene, Accession, CAS # | ABL1, Gene ID: 25, Accession: NP_005148.2 |
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| Catalog # | MBS717062 |
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| Order / More Info | Recombinant Human Tyrosine-protein kinase ABL1 from MYBIOSOURCE INC. |
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| Product Specific References | Nucleotide sequence of testis-derived c-abl cDNAsimplications for testis-specific transcription and abl oncogene activation.Oppi C., Shore S.K., Reddy E.P.Proc. Natl. Acad. Sci. U.S.A. 84:8200-8204(1987) Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation.Chissoe S.L., Bodenteich A., Wang Y.-F., Wang Y.-P., Burian D., Clifton S.W., Crabtree J., Freeman A., Iyer K., Jian L., Ma Y., McLaury H.-J., Pan H.-Q., Sarhan O.H., Tot |
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