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DDR1, Recombinant, Human, GST-Tag (CAK, CD167, DDR, EDDR1, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | DDR1, Recombinant, Human, GST-Tag (CAK, CD167, DDR, EDDR1, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE) |
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| Description | Purified (~70-90%). DDR1 is a member of the subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in its extracellular domain. DDR1 is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. Expression of DDR1 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain and DDR1 is over-expressed in fast-growing invasive tumors of the breast, ovary, esophagus, brain and lung. Collagen type I mediated stimulation of DDR1 leads to activation of matrix metalloproteinase 2 and 9 as well as increased cell invasion. Source: Recombinant protein corresponding to human DDR1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~77kD Specific Activity: 5nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_001954 |
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| Catalog # | 499925 |
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| Price | |
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| Order / More Info | DDR1, Recombinant, Human, GST-Tag (CAK, CD167, DDR, EDDR1, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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