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Product Name | Necrosis Inhibitor, Necrox-2 |
Description | A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1 µM NecroX-2 prevented ~50% cell death in H9C2 cells exposed to 400 µM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro. MW: 516.67. Purity ≥95% by HPLC |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(1-methanesulfonyl-piperidin-4-yl)-amine |
Gene, Accession, CAS # | n/a |
Catalog # | 2228-1 |
Price | |
Order / More Info | Necrosis Inhibitor, Necrox-2 from BIOVISION, INC. |
Product Specific References | n/a |
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