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Product Name | BGC 20-1531 hydrochloride |
Description | High affinity and selective EP4 antagonist (Ki = 3 nM). Exhibits >2500-fold selectivity for EP4 over EP2 and EP3. Also selective over a range of other prostanoid receptors, ion channels, transporters and enzymes. Inhibits PGE2-induced vasodilation of middle cerebral and meningeal arteries in vitro, and carotid blood flow in vivo. Orally bioavailable. Purity 98%. MW (observed): 529 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide hydrochloride. PGN 1531 |
Gene, Accession, CAS # | CAS: 1962928-26-2 |
Catalog # | 5327/10 |
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Order / More Info | BGC 20-1531 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 30397349 |
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