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| Product Name | Recombinant Human Interferon-induced, double-stranded RNA-activated protein |
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| Description | 2-551aa; Full Length. MW: 77.92kD. Purity >90% as determined by SDS-PAGE. IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV- |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Eukaryotic translation initiation factor 2-alpha kinase 2] |
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| Gene, Accession, CAS # | EIF2AK2, Gene ID: 5610, Accession: NP_001129123.1 |
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| Catalog # | MBS960175 |
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| Order / More Info | Recombinant Human Interferon-induced, double-stranded RNA-activated protein from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon.Meurs E., Chong K., Galabru J., Thomas N.S.B., Kerr I.M., Williams B.R.G., Hovanessian A.G.Cell 62:379-390(1990) Meurs E.Mechanism of interferon actioncDNA structure, expression, and regulation of the interferon-induced, RNA-dependent P1/eIF-2 alpha protein kinase from human cells.Thomis D.C., Doohan J.P., Samuel C.E.Virology 188:33-46(1992) Mechanism of interferon action sequen |
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