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| Product Name | NOG, Recombinant, Human, aa28-232, His-Tag (Noggin) |
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| Description | Purity ~90% (SDS-PAGE). NOG, also known as noggin, is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein(BMP)-signaling pathway. It binds several BMPs with very high affinities, with a marked preference for BMP2 and BMP4 over BMP7. It plays a key role in neural induction by inhibiting BMP4, along with other TGF-beta signaling inhibitors such as chordin and follistatin. Source: Recombinant protein corresponding to aa28-232 from human NOG, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~23.8kD (211aa), 28-40kD (SDS-PAGE under reducing conditions) AA |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005441 |
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| Catalog # | 369105 |
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| Order / More Info | NOG, Recombinant, Human, aa28-232, His-Tag (Noggin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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