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| Product Name | Migration Inhibitory Factor, Recombinant, Human |
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| Description | Purity ~ 97% as determined by N-terminus analysis and SDS-PAGE (silver stain). Macrophage migration inhibitory activity originally identified 30 years ago based on the ability to prevent the migration of guinea pig macrophages out of capillary tubes in vitro. A number of cytokines, including interferon-g and IL-4, exhibit macrophage migration inhibitory activity. A cDNA clone was isolated from a lectin-stimulated T-cell hybridoma cDNA library and reported to encode a protein with macrophage migration inhibitory activity. This protein was referred to as human migration inhibitory factor (MIF). MIF cDNA encodes a 115 amino acid residue polypeptide that lacks conventional hydrophobic leader sequence. MIF is expressed in many tissues and in all cell lines examined to date. MIF was also discovered as a growth factor-induced delayed early response gene DER6. Recently, MIF was reported to be a secreted cytokine that exerts a central and wide ranging role in host inflammatory responses. Eviden |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Migration Inhibitory Factor, Recombinant, Human (Macrophage MIF, Glycosylation-Inhibiting Factor, GIF, GLIF, MMIF) |
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| Gene, Accession, CAS # | Accession: NP_002406 |
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| Catalog # | M3895-07 |
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| Order / More Info | Migration Inhibitory Factor, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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