| 产品详情 |
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| Product Name | CIDE-A, CT, Blocking Peptide (Cell Death-inducing DFF-like Effector A) |
| Description | Purified 60-70%. Peptide corresponding to amino acids 200 to 217 of human CIDE-A (5). Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-4). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (5). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (5,6). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues. |
| Size | 50ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | C5072-01P |
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| Order / More Info | CIDE-A, CT, Blocking Peptide (Cell Death-inducing DFF-like Effector A) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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