| Edit |   |
|---|
| Antigenic Specificity | PEN2 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | n/a |
|---|
| Size | 0.1 mg |
|---|
| Concentration | IgG concentration 1.0mg/ml |
|---|
| Applications | Immunofluorescence (IF), Western Blot (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | RABBIT ANTI HUMAN PEN2 (C-TERMINAL). This item recognises Presenilin enhancer protein 2 (PEN), a 12 kDa member of the PEN2 family and subunit of the gamma-secretase complex. This complex is an endoprotease that cleaves integral membrane proteins. These include Notch receptors and the beta-amyloid precursor protein which is cleaved to form amyloid beta peptide, a major component of the neuritic plaques found in Alzheimer's disease. The gamma secretase complex consists of nicastrin, the presenilin |
|---|
| Immunogen | 13 amino acid peptide sequence near the carboxy terminus of human PEN2. |
|---|
| Other Names | gamma-secretase subunit PEN-2; Gamma-secretase subunit PEN-2; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; presenilin enhancer 2 homolog; presenilin enhancer gamma secretase subunit; Presenilin enhancer protein 2, PSENEN; PSENEN; PEN2; PEN-2; MDS033; MSTP064; PEN2 |
|---|
| Gene, Accession # | PEN2, Gene ID: 55851, NCBI: NP_001268461.1, UniProt: Q9NZ42 |
|---|
| Catalog # | MBS221484 |
|---|
| Price | |
|---|
| Order / More Info | PEN2 Antibody from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|