| 产品详情 |
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| Product Name | NS 6180 |
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| Description | Potent KCa3.1 channel blocker (IC50 values are 9, 14 and 15 nM for rat, human and mouse erythrocyte KCa3.1 channels respectively). Exhibits ~ 50% inhibition of KCa1.1, KV1.3, and KV11.1 channels, noradrenaline and dopamine transporters, L-type Ca2+ channels and melatonin receptors at a concentration of 10 μM. Potently inhibits IL-2 and IFN-γ production in rat lymphocytes (IC50 ~ 50 nM); reduces DBNS-induced experimental colitis in rats. Purity 99%. MW (observed): 323.33 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[3-(Trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one |
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| Gene, Accession, CAS # | CAS: 353262-04-1 |
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| Catalog # | 4864/50 |
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| Order / More Info | NS 6180 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26454020 |
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| 产品资料 |
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