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| Product Name | P32/98 (hemifumarate) |
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| Description | Purity >98%. The glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are responsible for a majority of nutrient-stimulated insulin secretion. After being released into the circulation, GIP and GLP-1 are inactivated by the circulating enzyme dipeptidyl peptidase IV (DPP IV). DPP IV inhibitors have emerged as a new class of experimental antidiabetic agents. P32/98 is a competitive transition-state substrate analog inhibitor of DPP IV (Ki = 126 nM). At 20 mg/kg/day, it has been used to improve glucose tolerance, insulin sensitivity, and Beta-cell glucose responsiveness in diabetic rat models. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,3S)-2-amino-3-methyl-1-(3-thiazolidinyl)-1-pentanone, 2E-butenedioate (2:1) |
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| Gene, Accession, CAS # | CAS: 251572-86-8 |
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| Catalog # | LS-H9234 |
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| Order / More Info | P32/98 (hemifumarate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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